You may qualify if you:

• Are 18–75 years old

• Have a Port-Wine Birthmark (PWB)

  • On the face or neck, or

  • On the arms, legs, trunk, or behind the ear

• Have a birthmark that is at least 3 cm x 2 cm in size

• Are in generally good health

• Have any skin tone (all skin types welcome)

Additional requirements:

• Participants must be able to give informed consent

• Women cannot be pregnant or breastfeeding

• Participants must agree to use birth control during the study (details explained by the study team)

• People with a history of seizures/epilepsy may be eligible if the condition has been stable for 6 months

  Study-related care provided
  IRB-approved clinical research study

This clinical trial will determine if taking an oral study medicine in combination with approved topical therapies can help to improve atopic dermatitis (eczema) in children who are 6 to 11 years old.

Your child may qualify if they:

• Are 6 to under 12 years old

• Have had eczema (atopic dermatitis) for at least 1 year

• Have moderate to severe eczema

• Have not had enough improvement with prescription topical treatments (such as steroid or non-steroid creams)

• Are candidates for systemic treatment

• Weigh at least 15 kg (33 lbs)

Additional information:

• Open to boys and girls

• Study-related care provided

• The study team will review medical history to ensure safety

IRB-approved pediatric clinical research study

Males or females at least 18 years old with stable nonsegmental vitiligo for at least 3 months

• Have moderate to severe plaque psoriasis

• Are a candidate for phototherapy or systemic treatment (including biologic therapy)

• Have at least one cardiovascular risk factor, such as:

  • Smoking

  • High blood pressure

  • High cholesterol

  • Diabetes (type 1 or 2)

  • Obesity

  • Personal history of heart attack, stroke, or other heart procedures

  • Family history of early heart disease or sudden cardiac death

You may qualify if you:

• Are an adult (18 y/o +) with subacute or chronic cutaneous lupus (including discoid lupus), confirmed by skin biopsy

• Have active skin lupus despite standard treatments

• Have moderate to severe skin involvement

• Test positive for at least one lupus-related autoantibody

What the study offers:

• Access to investigational treatment for skin lupus

• Study-related care and close monitoring by experienced clinicians

• Opportunity to contribute to advancing lupus research

We are looking for peri- and pre-menopausal women who:

• Have shallow nasolabial fold (smile line) wrinkles

• Have similar wrinkle severity on both sides of the face

• Can give informed consent for participation

• Agree to skin biopsies on the nasolabial folds

Exclusions:

• Significant wrinkle asymmetry

• Pregnant, planning pregnancy, or breastfeeding

• Allergies to treatment ingredients or lidocaine/anesthetics

Study-related care and monitoring provided

We are looking for adults interested in skin rejuvenation (face, neck and hands) to participate in a clinical research study evaluating the effectiveness and safety of next-generation Fraxel® FTX laser treatment for:

• Uneven skin tone or dyschromia

• Fine lines and periorbital wrinkles (crow’s feet)

• Sun-damaged skin or cutaneous lesions

Eligibility:

• Male or female, ages 21–60

• Moderate sun damage, wrinkles, or discoloration in the treatment area

• Able to read, understand, and sign informed consent

Exclusions:

• Pregnant, breastfeeding, or planning pregnancy during the study

• Allergic reaction to topical anesthetics

• Active skin conditions or infections in the treatment area (e.g., cold sores, burns, psoriasis, skin cancer)

• Recent cosmetic procedures in the target area (e.g., chemical peels, lasers, fillers, Botox)

• Conditions affecting the immune system (e.g., HIV, lupus, scleroderma)

• Recent use of certain medications (systemic or topical retinoids, steroids, immunosuppressants)

• Unprotected or recent sunburn on the treatment area

  Study-related care provided.